Dr. Chada Raji Reddy (CRR) Research Group
164. Chada Raji Reddy,* Karna Nair, Ejjirotu Srinivasu, Muppidi Subbarao, and René Grée
One-Pot Synthesis of N-Fused Benzimidazo-β-carbolines through Sequential Propargylation/aza-Cycloisomerization Approach
J. Org. Chem. 2024, 89, 4, 2675–2682
163. Chada Raji Reddy,* Agnuru Theja, Ejjirotu Srinivasu, and Muppidi Subbarao
Dearomative ipso-Cyclization to Spiropseudoindoxyls: An Extendable Approach To Access Indolo[3,2-c]quinolinones and Isocryptolepine
Org. Lett. 2024, 26, 1, 68–72
162. Chada Raji Reddy,* Ejjirotu Srinivasu, and Muppidi Subbarao
Seleno/Thio-functionalized ipso-Annulation of N-Propiolyl-2-arylbenzimidazole to Construct Azaspiro[5,5]undecatrienones
J. Org. Chem. 2023, 88, 23, 16485–16496
161. Chada Raji Reddy,* Sana Fatima, Dattahari H. Kolgave and Balasubramanian Sridhar
Radical-mediated sulfonylative/thiolative cyclization of biaryl enones to phenanthrone derivatives.
Org. Biomol. Chem., 2023, 21, 7327-733
160. Chada Raji Reddy,* Uprety Ajaykumar, Amol D. Patil and Remya Ramesh
ipso-Cyclization of unactivated biaryl ynones leading to thio-functionalized spirocyclic enones.
Org. Biomol. Chem., 2023, 21, 6379-6388
159. Baint Singh, Vishakha Goyal, Dhritismita Sarma, Raju Kumar, Tarun Bhatt, Arup Mahata*, Chada Raji Reddy, Anand Narani*, and Kishore Natte*
Earth-Abundant Heterogeneous Cobalt Catalyst for Selective Ring Hydrogenation of (Hetero)arenes and Gram-Scale Synthesis of Pharmaceutical Intermediates.
ACS Catal. 2023, 13, 14, 9724–9744
158. Chada Raji Reddy,* Veeramalla Ganesh, Nagender Punna
Aminative annulation of cyano-enynyl esters leading to functionalized cyclopentenones.
Chem. Commun., 2023, 59, 8600-8603
157. Chada Raji Reddy,* Muppidi Subbarao,† Anjali Rathaur,† and Ejjirotu Srinivasu
Rhodium(III)-Catalyzed [4+1] Oxidative Annulation of Amides with 1,3-enynes Through 1,4-Rhodium Migration
Adv. Synth. Catal. 2023, 365, 2036-2042
156. Chada Raji Reddy,* Uprety Ajaykumar, Dattahari H. Kolgave and Remya Ramesh
CAN-Promoted Thiolative ipso-Annulation of Unactivated N-Benzyl Acrylamides: Access to SCN/SCF3 /SO2 Ar Containing Azaspirocycles
J. Org. Chem. 2023, 88, 7117-7127
155. Chada Raji Reddy,* Ankita Kumari, Suraj Aswale, Amol D. Patil, and Y. Lakshmi Prapurna
Tandem 1,6-Addition/Annulations of Alkynyl p‐Quinone Methides with Bis-nucleophiles: Entry to Functionalized Furans, Isoxazoles, Pyrazoles, and Pyridines
J. Org. Chem. 2023, 88, 7046-7047
Synthesis of Ledipasvir through a Late-Stage Cyclopropanation and Fluorination Process
Synthesis, 2023, 55, in press
153. Chada Raji Reddy,* Karna Nair, Amol D. Patil, Ramachandra
Reddy Donthiri, René Grée
Domino alkyne insertion/aldol reaction/aromatization of 2- alkynyl indole-3-carbaldehyde with 1,3-diketones: Entry to 2- indolyl phenols
Org. Biomol. Chem. 2023, 21, 1046-1055
152. Chada Raji Reddy,* Roshan C. Kajare and Nagender Punna
Mn-mediated Radical Cascade Cyclization of 1,6-Enynes with Arylboronic Acids to access Dihydrobenzo[b]fluorenones
Adv. Synth. Catal. 2022, 364, 4409-4414
Structure Activity Relationship Studies around DB18, a Potent and Selective Inhibitor of CLK Kinases
Molecules 2022, 27, 6149
Access to diverse selenospirocyclohexadienones via Ag(II)-Catalyzed Selenylative ipso-Annulation with Se and boronic acids
ACS Omega 2022, 7, 38045-38052
149. Chada Raji Reddy,* Dattahari H. Kolgave, Uprety Ajaykumar
and Remya Ramesh
Copper(II)-Catalyzed Oxidative ipso-Annulation of N-Arylpropiolamides and Biaryl Ynones with 1,3-Diketones: Construction of Diketoalkyl Spirotrienones
Org. Biomol. Chem. 2022, 20, 6879 - 6889
148. Chada Raji Reddy,* Veeramalla Ganesh, Nagender Punna
Domino Aza-Annulations of Enynyl-/(Alkynyl)arylacetonitriles to Access Nitrogen- Enriched Heterocycles
J. Org. Chem. 2022, 87, 11547-11557
Discovery of potent dual ligands for Dopamine D4 and σ1 receptors
Bioorg. Med. Chem. 2022, 69, 116851
146. Chada Raji Reddy,* Ketan Wadekar, Karna Nair, Y. Lakshmi Prapurna
A sequential cycloisomerization/ oxidative aromatization of 2- propargyl cyclohexenones for direct access to substituted benzofurans
Synthesis 2022, 54, 4503-4508
145. Chada Raji Reddy,* Mayur C. Bhandari, Amol D. Patil, Mounika Aila, and Ramchandra Reddy D
FeCl3-Mediated selenylative benzannulation of aryl alkynones to 3-selenyl -naphthols
Org. Biomol. Chem 2022, 20, 4765-4772
A strategy for the Synthesis of Bicyclic Fused Cyclopentenones from MBH-Carbonates of Propiolaldehydes
Synthesis 2022, 54, 3623–3630
Total Synthesis of Remdesivir
Tetrahedron Lett. 2022, 88, 153590
142. Chada Raji Reddy and Dattahari H. Kolgave
Electrochemical Selenylative Carbannulation of Biaryl Ynones to Seleno-Dibenzocycloheptenones/Spiro[5.5]Trienones
J. Org. Chem. 2021, 86, 23, 17071–17081
141. AV Ramana Murthy, V Narendar, N Sampath Kumar, Pasula Aparna, AKD Bhavani, H Solhi, RL Guevel, Julie Roul, Fabien Gautier, Philippe Juin, Chada Raji Reddy, Paul Mosset, Nicolas Levoin,* René Grée*
Synthesis and biological studies of new piperidino-1,2,3-triazole hybrids with 3-aryl isoxazole side chains
Bioorg. Med. Chem. Lett. 2021, 52, 128390
140. Saqlain Haider, Pankaj Pandey, Chada Raji Reddy, Lanet A Lambert and Amar Chittiboyina*
Novel Machaeriol Analogues as Modulators of Cannabinoid Receptors: Structure–Activity Relationships of (+)-Hexahydrocannabinoids and Their Isoform Selectivities
ACS Omega 2021, 6, in press
139. Andhavaram Ramaraju, Atul Upare, Ewan W. Blanch, Subashani Maniam, Balasubramanian Sridhar, Surendar Reddy Bathula and Chada Raji Reddy*
Chemoselective [3+2] annulation of oxime acetate with 2-aryl-3-ethoxycarbonyl-pyrroline-4,5-dione: Entry to pyrrolo[2,3-b] pyrrole derivatives
Org. Biomol. Chem 2021, 19, in press
138. Chada Raji Reddy, Mounika Aila, Muppidi Subbarao, Kamalkishor Warudikar and René Grée
Domino Reaction of 2,4-Diyn-1-ols with 1,3-Dicarbonyl Compounds: Direct Access to Aryl/Heteroaryl-Fused Benzofurans and Indoles
Organic Letters,
137. Chada Raji Reddy,*and Amol D. Patil
Iodo- and Chalcogenoannulation of Morita–Baylis–Hillman Alcohols of Propiolaldehydes: Entry to Functionalized 2-Pyrones
Organic Letters,
Org. Lett. 2021, 23, 12, 4749–4753
136. D. Brahmaiah, A. K. Durga Bhavani, P. Aparna, N. Sampath Kumar, Helene Solhi, R Le Guevel, B. Baratte, S. Ruchaud, S. Bach, Surender S. J, Ch. Raji Reddy, Thierry Roisnel, Paul Mosset , N. Levoin, Rene Gree
Discovery of DB18, a potent inhibitor of CLK kinases with a high selectivity against DYRK1A kinase
Bioorg. Med. Chem Letters, 2021, 31, 115962
135. Chada Raji Reddy* Roshan Chandrakant Kajare, Mayur C. Bhandari, Siddique Z. Mohammed, Mahender khatravath,Kamalkishor Warudikar and Nagender Punna
Facile access to [1,2]-oxazine derivatives via annulations of aminoxy-tethered 1,7-enynes
Org. Biomol. Chem, 2021, 19, 809-821
134. Chada Raji Reddy,* Srinivas Bodasu, Kathe Mallesh and Y. Lakshmi Prapurna
Synthesis of Fused Pyrimido[1,6-a]indolones via Rh(III)-Catalyzed Cascade Annulations,
Synthesis, 2021, 53, 1127 - 1136
133. Chada Raji Reddy,* Ejjirotu Srinivasu, Puppala Sathish, M. Subbarao, and Ramachandra Reddy Donthiri
One-pot arylative benzannulation of 2-formyl-3-propargyl indoles with boronic acids leading to 3,4-diaryl carbazoles
J. Org. Chem. 2021, 86, 1118-1132
132. Chada Raji Reddy,* Uprety Ajaykumar and Dattahari H. Kolgave
Expeditious Access to Spiro-fused 2,5-Cyclohexadienones via Thio(seleno)cyanative ipso-Cyclization
J. Org. Chem. 2020, 85, 15521-15531
131. Avula Shiva Krishna, Shalini B., Rajesh N., Chada Raji Reddy, G. Sudhakar, Srihari P.,Prathama Mainkar, Kumaraguru T., Subhash Ghosh and S. Chandrasekhar
Chemo-enzymatic process for the preparation of (S)-7-((tert-butyldiphenylsilyl)oxy) hept-1-yn-4-ol in a continuous packed-bed reactor (PBR), a key intermediate for Eribulin synthesis
Org. Process. Res. Dev. 2020, 24, 2657-2664
130. Chada Raji Reddy,* Puppala Sathish, Kathe Mallesh and Y. Lakshmi Prapurna
Construction of Unique Polycyclic 3, 4-Fused Indoles via Rhodium(III)-Catalyzed Domino Annulations
Chemistry Select 2020, 5, 12736–12739
129. Chada Raji Reddy,* and Sudam N Sinare
Expedient approach to the synthesis of betrixaban
SynOpen 2020, 4, 62-65
128. Chada Raji Reddy,* Veeramalla Ganesh and Ajay K Singh
Photo-flow controlled E-Z isomeric motion of the functionalized 3-benzylidene-indolin-2-ones
RSC Adv. 2020, 10, 28630-28634
127. Chada Raji Reddy,* Dattahari H. Kolgave, Muppidi Subbarao, Mounika Aila and Santosh K. Prajapti
Ag-Catalyzed Oxidative ipso-Cyclization via Decarboxylative Acylation/Alkylation: Access to 3-Acyl/Alkylspiro[4.5] trienones
Organic Letters 2020, 22, 5342-5346
126. Chada Raji Reddy,* Amol D. Patil and Siddique Z. Mohammed
Oxa-[3+3] Annulation of MBH-Carbonates of Propiolaldehydes with -Nitro/Bromo Ketones to Access 2H-Pyrans
Chem. Commun. 2020, 56, 7191-7194
125. Chada Raji Reddy,* Kathe Mallesh, Bodasu Srinivas and Ramachandra Reddy Donthiri
Rh(III)-Catalyzed Domino [4+2] Annulation/aza-Michael Addition of N-(pivaloyloxy)benzamides with 1,5-Enynes via C-H Activation: Synthesis of Functionalised Aromathecins
J. Org. Chem. 2020, 85, 7905-7915
124. Chada Raji Reddy,* Roshan Chandrakant Kajare and Nagender Punna
Silver-catalyzed acylative annulation of N-propargylated indoles with α-keto acids: Access to acylated pyrrolo[1,2-a]indoles
Chem. Commun. 2020, 56, 3445-3448
123. Chada Raji Reddy,* Muppidi Subbarao, Puppala Sathish, Dattahari H. Kolgave and Ramachandra Reddy Donthiri
One-pot Assembly of 3-Hydroxycarbazoles via Uninterrupted Propargylation/ Hydroxylative Benzannulation Reactions
Organic Letters 2020, 22, 689-693
122. Chada Raji Reddy,* Mounika Aila, Puppala Satish, Madoori Mrinalini, Giribabu Lingamallu, Seelam Prasanthkumar and Rene Gree
Metal-free Propargylation/aza-Annulation Approach to Substituted - Carbolines and Evaluation of their Photophysical Properties
Org. Biomol. Chem 2019, 17, 9291-9304
121. Chada Raji Reddy* Kathe Mallesh Gajula Dharmapuri Uredi Dilipkumar
Total Synthesis of Pandangolide 1 Proposed Structure
Synth Commun 2019, 49, 2709-2716
120. Chada Raji Reddy,* Puppala Satish and Reddi Rani Valleti
A Facile Approach to 3,4‐Oxepino‐Fused Tricyclic Indoles from MBH‐Acetates of Acetylenic Aldehydes via Successive Allylic Substitution/Intramolecular [3+2] Annulation
Chemistry Select 2019, 4, 8229-8232
119. Chada Raji Reddy* Kamalkishor Warudikar and Bellamkonda Latha
Facile strategy to access the indolo[2,3-a]quinolizidine framework: Synthetic study on tangutorine
Synthesis 2019, 51, 3715-3722
118. Chada Raji Reddy* and Amarender Goud Burra
[4+2]-Annulation of MBH-Acetates of Acetylenic Aldehydes with Imidazoles/Benzimidazoles to Access Imidazo[1,2-a]pyridines /Benzimidazo[1,2-a]pyridines
J. Org. Chem. 2019, 84, 9169-9178
117. Chada Raji Reddy,* Siddique Z. Mohammed, Gaddam Krishna and Y. Lakshmi Prapurna
Synthesis of the Southern Furan Segment of Furanocembranoids
Synth Commun 2019, 49, 1153-1158
116. Chada Raji Reddy* Ravi Ranjan and Santosh Kumar Prajapti
Copper-Catalyzed Intramolecular Chalcogenoamination of Enynyl Azides: Synthesis of 5- Selenyl/Sulfenyl Nicotinates
Organic Letters 2019, 21, 623-626
115. Chada Raji Reddy* Kamalkishor Warudikar and Balasubramanian Sridhar
Synthetic Access to Cyclopenta[a]inden-2(1H)-ones from Morita-Baylis-Hillman Products of 2-Alkynyl Benzaldehydes
ACS Omega 2018, accepted
114. Chada Raji Reddy* and Siddique Z. Mohammed
Synthetic Studies toward (±)-Furanocembranoid 1: Construction of the Acyclic
Carbon Framework
ACS Omega 2018, accepted
113. Chada Raji Reddy* Muppidi Subbarao, J. Vijaykumar, Surender S. Jadav, Nilesh Sasane, Reddi Rani Valleti, Bhukya Supriya, and Ramesh Ummanni*
One Pot Synthesis of Triazolo-Heterolignans: Biological Evaluation and Molecular Docking Studies as Tubulin Inhibitors
Anti-Cancer Agents in Med. Chem., 2018, accepted
112. Chada Raji Reddy* Santosh Kumar Prajapti and Ravi Ranjan
Cu(I)-Catalyzed Aminative aza-Annulation of Enynyl Azide using N-Fluorobenzenesulfonimide (NFSI): Synthesis of 5-Amino Nicotinates
Organic Letters 2018, 20, 3128-3131
111. Chada Raji Reddy* Amol G. Tukaram, Siddique Mohammed, Uredi Dilipkumar, B. Nagendra Babu, Sumana Chakravarty* D. Bhattacharya, Pranav C. Joshi and René Grée
Synthesis and biological evaluation of Longanlactone analogues as neurotrophic agents
Bioorg. Med. Chem. Lett 2018, 28, 673-676
110. Chada Raji Reddy* and Kathe Mallesh
Rh(III)-Catalyzed Cascade Annulations to Access Isoindolo[2,1-b]isoquinolin-5(7H)-ones via C−H Activation: Synthesis of Rosettac
Organic Letters 2018, 20, 150-153
109. Chada Raji Reddy,* Ravi Ranjan, Santosh Kumar Prajapti and Kamalkishor Warudikar
One-Pot Consecutive Sulfonamidation/ipso-Cyclization Strategy for the Construction of Azaspirocyclohexadienones.
J. Org. Chem. 2017, 82, 6932-6939
108. Chada Raji Reddy,* Santosh Kumar Prajapti, Kamalkishor Warudikar, Ravi Ranjan and Billa Bhargava Rao
Ipso-Cyclization: An Emerging Tool for Multifunctional Spirocyclohexadienones
Org. Biomol. Chem. 2017, 15, 3130-3151
107. Chada Raji Reddy,* Reddi Rani Valleti and Puppala Sathish
[4+2]-Benzannulation of 3-alkenyl-pyrroles/thiophenes with propargylic alcohols: Access to Substituted Indoles, Benzothiophenes and Aza[5]helicenes
J. Org. Chem. 2017, 82, 2345-2354
106. Chada Raji Reddy,* Uredi Dilipkumar and Ravula Shravya
Atom- and Pot-Economical Consecutive Multi-Step Reaction Sequence to Poly Aromatic Hydrocarbons (PAHs)
Chem. Commun. 2017, 53, 1904-1907
105. Chada Raji Reddy,* Sujatarani A. Panda and A Ramaraju
Oxidative Aza-Annulation of Enynyl Azides to 2-keto/formyl pyrroles
J. Org. Chem. 2017, 82, 944-949
104. Chada Raji Reddy,* Palacherala Ramesh, and Bellamkonda Latha
Formal Syntheses of 5, 8-Disubstituted Indolizidine Alkaloids, (-)-205A, (-)-207A and (-)-235B
Synlett 2017, 28, 481-484
103. Chada Raji Reddy,* Amarender Goud B, Kiran K. Singarapu and René Grée
Facile entry to 3,4-dihydro-1H-pyrrolo[2,1,c][1,4]-oxazines via the oxa-Pictet-Spengler reaction
Eur. J. Org. Chem. 2016, 5274-5281
102. Chada Raji Reddy* Uredi Dilipkumar, Kathe Mallesh, Bellamkonda Latha and Ravula Shravya
Total Synthesis of (+)-cladospolide D
Tetrahedron: Asymmetry, 2016, 27, 222-225
101. Chada Raji Reddy*, Reddi Rani Valleti and Uredi Dilipkumar
One-pot sequential propargylation/Cycloisomerization: A facile [4+2]-benzannulation approach to carbazoles
Chem. Eur. J. 2016, 22, 2501-2506.
100. Chada Raji Reddy* Bellamkonda Latha, Kamal Kishore Warukar and Kiran Kumar Singarapu
Total Synthesis of a piperidine alkaloid, Microcosamine A
Org. Biomol. Chem. 2016, 14, 251-258.
99. Utpal Bhadra, Tanmoy Mondal, Indira Bag, D. Mukhopadhyay, P. Das, B. B. Parida, Prathama S. Mainkar, Chada Raji Reddy and Manika Pal Bhadra*
HDAC-Inhibitor misprocesses bantam oncomi RNA, but stimulates hid induced apoptotic pathway
Scientific Reports. 2015, 14747
98. Chada Raji Reddy* Siddique Z Mohammed and Paridala Kumaraswamy
A [3+2]-annulation approach to tetrasubstituted furans from MBH-Carbonates of acetylenic aldehydes via sequencial substitution/cycloisomerization
Org. Biomol. Chem. 2015, 13, 8310-8321.
97. Chada Raji Reddy* Devatha Suman and Nagavaram Narsimha Rao
Alkyne-mediated approach to the synthesis of (4R, 5R)-5-hydroxy-4-decanolide and (-)-muricatacin
Helv. Chim. Acta, 2015, 98, 967-972.
96. Chada Raji Reddy* Sujatarani A Panda and Motatipally Damoder Reddy
Aza-Annulation of Enynyl Azides: A New Approach to Substituted Pyridines
Organic Letters, 2015, 17, 896-899.
95. N. Nagesh, G. Raju, R. Srinivas, P. Ramesh, M. Damoder Reddy and Chada Raji Reddy*
A dihydroindolizino indole derivative selectively stabilizes G-quaduplex DNA and down-regulates c-MYC expression in human cancer cells
Biochimica et Biophysica Acta, 2015, 1850, 129-140.
94. Chada Raji Reddy* Palacherla Ramesh and Nagavaram Narsimha Rao
Synthesis of the Highly Stereocentered (C8-C16) fragment of Amphidinolide R
Tetrahedron: Asymmetry, 2014, 25, 1532-1536.
93. Chada Raji Reddy* Motatipally Damoder Reddy and Uredi Dilipkumar
Total synthesis of a pyrrole lactone alkaloid, Longanlactone
Eur. J. Org. Chem. 2014, 6310-6313
92. Chada Raji Reddy* Paridala Kumaraswamy and Kiran K. Singarapu
Sequential allylic substitution/Pauson-Khand reaction: A strategy to bicyclic fused cyclopentenones from MBH-acetates of acetylenic aldehydes
J. Org. Chem. 2014, 79, 7880-7888.
91. Chada Raji Reddy* Uredi Dilipkumar and Motatipally Damoder Reddy
A Novel [4+2]-benzannulation to access substituted benzenes, polycyclic aromatic and benzenefused heteroaromatic compounds
Organic Letters, 2014, 16, 3792-3795.
90. Chada Raji Reddy* Ravi Ranjan, Paridala Kumaraswamy, Motatipally Damoder Reddy and Rene Gree
1-Aryl propargylic alcohols as handy synthons for the construction of heterocycles and carbocycles
Curr. Org. Chem. 2014, 18, 2603-2645.
89. David J. Weldon, Falgun Shah, Amar G. Chittiboyina, Anjaneyulu Sheri, Raji Reddy Chada,
Jiri Gut, Philip J. Rosenthal, Develeena Shivakumar, Woody Sherman, Prashant Desai,
Jae-Chul Jung, Mitchell A. Avery*
Synthesis, biological evaluation, hydration site thermodynamics, and chemical reactivity analysis of a-keto substituted peptidomimetics for the inhibition of Plasmodium falciparum
Bioorg. Med. Chem. Lett. 2014, 24, 1274-1279
88. G. Raju, R. Srinivas, M. Damoder Reddy, Chada Raji Reddy and N. Nagesh*
Studies on non-covalent interaction of coumarin attached pyrimidine and 1-methyl indole 1,2,3-triazole analogues with intermolecular telomeric G-quadruplex DNA using ESI-MS and spectroscopy
Nucleosides, Nucleotides and Nucleic Acids 2014, 33, 489-506
87. Chada Raji Reddy* Enukonda Jithender, Ashita Singh and Ramesh Ummanni
Stereoisomers of ieodoglucomides A and B: Synthesis and evaluation of anticancer activity
Synthesis 2014, 46, 822-827
86. Chada Raji Reddy* Gaddam Krishna and Motatipally Damoder Reddy
Synthesis of substituted 3-furoates from MBH-acetates of acetylenic aldehydes via tandem isomerization/deacetylation/cycloisomerization: access to Elliott’s alcohol
Org. Biomol. Chem. 2014, 12, 1664-1670.
85. Chada Raji Reddy* and Paridala Kumaraswamy
Copper-promoted cascade reaction of active methylenes with MBH-acetates of acetylenic aldehydes to functionalized cyclopentenes
RSC Advances 2014, 4, 7035-7040.
84. Chada Raji Reddy* and Motatipally Damoder Reddy
A Metal-Free Tandem C-C/C-O bond Formation Approach to Diversely Functionalized Tetrasubstituted Furans
J. Org. Chem. 2014, 79, 106-116.
83. Jerald Mahesh, Chada Raji Reddy and Narayana Nagesh*
Phenyl 1,2,3-triazole thymidine ligands stabilize G-quadruplex DNA, inhibit DNA synthesis and potentially reduce tumor cell proliferation over 3’Azido deoxythymidine
PLoS One 2013, 8, e70798
82. Chada Raji Reddy* Reddi Rani Valleti and Motatipally Damoder Reddy
A thioannulation approach to substituted thiophenes from Morita-Baylis-Hillman acetates of acetylenic aldehydes
J. Org. Chem. 2013, 78, 6495-6502.
81. Chada Raji Reddy* Devatha Suman and Nagavaram Narsimha Rao Alkyne-mediated approach for total synthesis of Cladospolide A, B, C and iso-cladospolide B
Eur. J. Org. Chem. 2013, 3786-3796.
80. Chada Raji Reddy* Enukonda Jithender and Kothakonda Rajendra Prasad,
Total syntheses of the Proposed Structure for Ieodoglucomides A and B
J. Org. Chem. 2013, 78, 4251-4260.
79. Chada Raji Reddy* Uredi Dilipkumar, Motatipally Damoder Reddy and Nagavaram Narsimha Rao
Total synthesis and revision of the absolute configuration of seimatopolide B
Org. Biomol. Chem. 2013, 11, 3355-3364.
78. Chada Raji Reddy* Jonnalagadda Vijaykumar and René Grée
Facile one-pot access to 3,5-disubstituted 1H-pyrazoles from propargylic alcohols via propargyl hydrazides
Synthesis 2013, 45, 830-836.
77. Chada Raji Reddy* and G. Dharmapuri
Stereoselective synthesis of the C10-C18 fragment of iriomoteolide 3a
Synthesis 2013, 45, 673-677.
76. Chada Raji Reddy* Boyinapally Srikanth, Uredi Dilipkumar, K. Veera Mohana Rao and B. Jagadeesh
Total synthesis of a 6,6-spiroketal metabolite, dinemasone A
Eur. J. Org. Chem. 2013, 525-532.
75. Chada Raji Reddy,* Paridala Kumaraswamy and Motatipally Damoder Reddy
Tandem allylic substitution/5-exo-dig-carbocyclization: A [4+1]-annulation approach to arylidene cyclopentenes from MBH-acetates of acetylenic aldehydes
Org. Biomol. Chem. 2012, 10, 9052-9057.
74. Chada Raji Reddy,* Motatipally Damoder Reddy and Kothapalli Haribabu
Organocatalyzed intramolecular-Michael addition of Morita-Baylis-Hillman adducts of β-aryl nitroethylenes: an entry to 3-aryl 4-nitrocyclohexanones
Eur. J. Org. Chem. 2012, 6414-6419.
73. Chada Raji Reddy,* Jonnalagadda Vijaykumar, Enukonda Jithender, Gangireddy Pavan Kumar Reddy and Rene Gree
One-pot access to 3, 5-disubstituted isoxazoles from propargylic alcohols through propargylic N-hydroxylamines
Eur. J. Org. Chem. 2012, 5767-5773.
72. Chada Raji Reddy,* Gaddam Krishna, N. Kavitha, B. Latha and Dong-Soo Shin
Access to 2, 3-disubstituted benzofurans via one-pot acid-catalyzed nucleophilic substitution/TBAF-mediated oxacycloisomerization
Eur. J. Org. Chem. 2012, 5381-5388
71. Chada Raji Reddy,* Nagavaram Narsimha Rao and Motatipally Damoder Reddy
Total synthesis of (+)-seimatopolide A
Eur. J. Org. Chem. 2012, 4910-4913.
70. Chada Raji Reddy* and Nagavaram Narsimha Rao,
Formal total synthesis of (-)-exiguolide
RSC Advances. 2012, 2, 7724-7734.
69. Chada Raji Reddy* Nagavaram Narsimha Rao, Pombala Sujitha and Chityal Ganesh Kumar
Protecting-group-free synthesis of (4S, 5S, 11R) and (4S, 5S, 11S)-iso-cladospolide B and their biological evaluation
Synthesis 2012, 1663-1666.
68. Chada Raji Reddy,* Motatipally Damoder Reddy and Boyinapally Srikanth
Phosphine-mediated cascade reaction for substituted pyrroles: A facile access to N-fused pyrrolo-heterocycles
Org. Biomol. Chem. 2012, 10, 4280-4288.
67. Chada Raji Reddy* Nagavaram Narsimha Rao, Pombala Sujitha and Chityal Ganesh Kumar
Total synthesis of (+)-aspicilin employing an alkyne-based approach and it’s biological evaluation
Eur. J. Org. Chem. 2012, 1819-1824.
66. Chada Raji Reddy* Devatha Suman and Nagavaram Narsimha Rao
Alkyne-assisted approach to the formal synthesis of a macrolide antibiotic, A2677B1
Synlett 2012, 272-274.
65. S. Chandrasekhar* NCVL Puspavalli, Srinivas Chatla, D. Mukhopadhyay, Bogonda Ganganna, Kandi Vijeender, Pabbaraja Srihari, Chada Raji Reddy, M. Janaki Ramaiah and Utpal Bhadra
Aza-flavanones as potent cross-species microRNA inhibitors that arrest cell cycle
Bioorg. Med. Chem. Lett. 2012, 22, 645-648.
64. Chada Raji Reddy,* Bellamkonda Latha and Nagavaram Narsimha Rao
Enantioselective access to (-)-indolizidines 167B, 209D, 195B, 239AB and (-)-monomorine from a common chiral synthon
Tetrahedron 2012, 68, 145-151.
63. Chada Raji Reddy* and Bellamkonda Latha
Synthesis of (-)-Dihydropinidine, (2S, 6R)-Isosolenopsin and (+)-Monomorine via a chiral synthon from L-Aspartic acid
Tetrahedron: Asymmetry 2011, 22, 1849-1854.
62. Chada Raji Reddy* G. Balakrishna Reddy and B. Srikanth
Stereo-selective Synthesis of a Tetrahydropyranyl Diarylheptanoid,ent-Diospongin A
Tetrahedron: Asymmetry, 2011, 22, 1725-1728.
61. Chada Raji Reddy,* L. Radhika, T. Pavan Kumar and S. Chandrasekhar
First acid-catalyzed entry to O-alkylated hydroximides from benzylic alcohols
Eur. J. Org. Chem. 2011, 5967-5970
60. S. Chandrasekhar,* B. V. D. Vijaykumar, B. Mahesh Chandra Ch. Raji Reddy and P. Naresh
Flow chemistry approach for partial deuteration of alkynes: Synthesis of deuterated taxol side chain
Tetrahedron Letters, 2011, 52, 3865-3867.
59. S. Chandrasekhar,* T. Pavan Kumar, K. Haribabu, Ch. Raji Reddy and Ch. Ramesh Kumar
A chiral pyrrolidine-pyrazole catalyst for the enantioselective Michael addition of carbonyls to nitroolefins
Tetrahedron: Asymmetry 2011, 22, 697-702.
58. Ch. Raji Reddy,* M. Damoder Reddy, B. Srikanth and K. Rajendra Prasad
Morita-Baylis-Hillmann acetates of acetylenic aldehydes: Versatile synthons for substituted pyrroles via a metal-free tandem reaction
Org. Biomol. Chem. 2011, 9, 6027-6033.
57. Ch. Raji Reddy,* E. Jithender, G. Krishna, E. Venkat Reddy and B. Jagadeesh
A novel acid-catalyzed C5-alkylation of oxindoles using alcohols
Org. Biomol. Chem. 2011, 9, 3940-3947.
56. Ch. Raji Reddy,* P. Ramesh, N. Narsimha Rao and Syed Aziz Ali
A facile synthesis of substituted dibenzoxepines using an acid-catalyzed tandem reaction
Eur. J. Org. Chem. 2011, 2133-2141.
55. S. Chandrasekhar,* M. Seenaiah, A. Kumar, Ch. Raji Reddy, Suman Kumar, M., C. Ganesh Kumar
Intramolecular copper(I)-catalyzed 1, 3-dipolar cycloaddition of azido-alkynes: Synthesis of triazolo- benzoxazepine derivatives as anti-microbial agents
Tetrahedron Letters, 2011, 52, 806-808
54. Ch. Raji Reddy, P. Phani Madhavi and S. Chandrasekhar,*
Stereoselective synthesis of tetrahydropyranyl diarylheptanoids (-)-Centrolobine and (+)-Centrolobine
Synthesis, 2011, 123-126.
53. Ch. Raji Reddy,* and N. Narsimha Rao
Synthesis of the methylene bis-tetrahydropyran motif of (-)-Exiguolide Tetrahedron Letters, 2010, 51, 5840-5842.
52. S. Chandrasekhar,* T. Pavankumar, K. Haribabu and Ch. Raji Reddy Hydroxyphthalimide allied triazole-pyrrolidine catalyst for asymmetric Michael addition in water
Tetrahedron: Asymmetry, 2010, 21, 2372-2375.
51. Ch. Raji Reddy,* J. Vijaykumar and Rene Gree
Tris(pentafluorophenyl)borane–catalyzed alkylation of 1,3–dicarbonyl compounds with benzylic alcohols: Access to oxygenated Heterocycles
Synthesis, 2010, 3715-3723.
50. Ch. Raji Reddy,* and B. Srikanth
Synthesis of the tetrahydropyran subunit (C8-C20 fragment) of (-)-Dactylolide/(-)-Zampanolide
Synlett, 2010, 1536-1538.
49. Ch. Raji Reddy,* P. Phani Madhavi and S. Chandrasekhar
Synthesis of a diarylheptanoid, (+)-Centrolobine
Tetrahedron: Asymmetry, 2010, 21, 103-105.
48. Ch. Raji Reddy,* N. Narsihma Rao and B. Srikanth
Total synthesis of a diaryl heptanoid, Rhoiptelol B
Eur. J. Org. Chem. 2010, 345-351
47. Ch. Raji Reddy,* G. Dharmapuri and N. Narsimha Rao Synthesis of the Macrocyclic core of Iriomoteolide 3a
Organic Letters, 2009, 11, 5730-5733.
46. S. Chandrasekhar,* Sanjida Khatun, G. Rajesh and Ch. Raji Reddy
B(C6F5)3: An efficient catalyst for reductive alkylation of alkoxy benzenes and for synthesis of triarylmethanes using aldehydes Tetrahedron Letters, 2009, 50, 6693-6697.
45. S. Chandrasekhar,* G. S. Kiran Babu and Ch. Raji Reddy
Asymmetric synthesis of aza-diospongin A as a novel iNOS inducer
Tetrahedron: Asymmetry, 2009, 20, 2216-2219.
44. S. Chandrasekhar,* R. V. N. S. Murali and Ch. Raji Reddy Enantioselective synthesis of (-)-Lasubine II
Tetrahedron Letters, 2009, 50, 5686-5688.
43. Ch. Raji Reddy* and E. Jithender
Acid-catalyzed N-alkylation of tosylhydrazones using benzylic alcohols
Tetrahedron Letters, 2009, 50, 5633-5635.
42. S. Chandrasekhar,* K. Johny and Ch. Raji Reddy
Proline-threonine dipeptide as an organocatalyst for direct asymmetric aldol reaction
Tetrahedron: Asymmetry, 2009, 20, 1742-1745
41. Ch. Raji Reddy,* and N. Narsimha Rao
An efficient total synthesis of (+)-Cladospolide C
Tetrahedron Letters, 2009, 50, 2478-2480.
40. Ch. Raji Reddy,* N. Kiranmai, K. Johny, M. Pendke and P. Naresh
Nucleophilic addition of 4-hydroxycoumarin on Baylis-Hillman acetate adducts
Synthesis, 2009, 399-402.
39. Zuo Hua, K-H. Kam, H-J. Kwon, L. Meng, Ch. Ahn, T-J. Won, T-H. Kim, Ch. Raji Reddy, S. Chandrasekhar and Dong-Soo Shin,*
Microwave-assisted synthesis of 2H-Benzo[b][1,4]oxazin-3(4H)-ones and 1H-Pyrido[2,3-b] [1,4]oxazin- 2(3H)-ones via Smiles Rearrangement
Bull. Korean Chem. Society, 2008, 29, 1379-1385.
38. Ch. Raji Reddy,* B. Srikanth, N. Narsihma Rao and Dong-Soo Shin
Solid supported acid-catalyzed C3-alkylation of 4-hydroxy coumarins with secondary benzyl alcohols: access to synthesis of 3, 4-disubstituted coumarins via Pd-coupling
Tetrahedron, 2008, 64, 11666-11672.
37. S. Chandrasekhar,* M. Seenaiah, Ch. Lohitha Rao and Ch. Raji Reddy
A smooth access to benzotriazoles via azide-alkyne cycloaddition Tetrahedron, 2008, 64, 11325-11327.
36. Ch. Raji Reddy,* P. Phani Madhavi and S. Chandrasekhar Asymmetric synthesis of 6-epi- (-)-Centrolobine
Synthesis, 2008, 2939-2942.
35. Ch. Raji Reddy,* N. Narsimha Rao and A. Sudhakar
Exploring the catalytic activity of MoCl5 as a Lewis acid in various C-C bond formation reactions
Letters in Organic Chemistry, 2008, 5, 473-477.
34. uo Hua, Meng Lijuan, Manjunath Ghate, Kyu-Hyeon Hwang, Young Kweon Cho, S. Chandrasekhar, Ch. Raji Reddy and Dong-Soo Shin,*
Microwave-assisted one-pot synthesis of benzo[b][1,4]oxazin -3(4H)-ones via Smiles rearrangement
Tetrahedron Letters , 2008, 49, 3827-3830
33. S. Chandrasekhar,* B. Saritha, T. Naresh, M. Udaykiran, Ch. Raji Reddy and B. Jagadeesh,*
Hybrid cyclic peptide based on cis-b-furanoid sugar amino acid (FSAA) and ornithine: Formation of macro cavity stabilized by 6/7-membered hydrogen bonded rings
Helv. Chim. Acta, 2008, 91, 1267-1276.
31. S. Chandrasekhar,* Y. Srinivasa Rao , A. Sreelakshimi and Ch. Raji Reddy Formal total synthesis of (-)-Spongidepsin
Tetrahedron, 2008, 64, 5174-5183.
30. S. Chandrasekhar,* Bhoopendra Tiwari, Bhusan B. Parida and Ch. Raji Reddy
Chiral pyrrolidine-triazole conjugate catalyst for asymmetric Michael and Aldol reactions
Tetrahedron: Asymmetry, 2008, 19, 495-499
29. Ch. Raji Reddy,* B. Mahipal and Y. Srinivasa Rao
Lewis acid catalyzed N-acylation of carbamates and oxazolidinones
Arkivoc, 2008, 250-257.
28. Ch. Raji Reddy,* G. Rajesh, S. V. Balaji and N. Chethan Tris(pentafluorophenyl) borane: A mild and efficient catalyst for the chemoselective tritylation
Tetrahedron Letters, 2008, 49, 970-973.
27. Ch. Raji Reddy,* G. Balakrishna Reddy and Ch. Lohitha Rao
Titanium tetrachloride mediated reductive ring opening of C-aryl pseudoglycals
Tetrahedron Letters, 2008, 49, 863-866.
26. J. Kang, K. H. Kam, Manjunath Ghate, Zho Hua, Tae-Hyun Kim, Ch. Raji Reddy, S. Chandrasekhar and Dong-Soo Shin,*
An Efficient Synthesis of 2H-1,4-benzoxazine 3-(4H)-ones via Smiles Rearrangement
Arkivoc, 2008, 67-76.
25. Ch. Raji Reddy,* Y. Srinivasa Rao, T. Pavan Kumar, K. Vankatram Reddy and S. Chandrasekhar
Hydroxylamine derivatives as nucleophiles in Ferrier glycosylation: Synthesis of aminoxy pseudoglycals
Synthesis, 2008, 122-126.
24. Gyeonghyeon Gim, Meng Lijuan, Zuo Hua, Manjunath Ghate, Chuljin Ahn, Tae-Jin Won, Tae-Hyun Kim, Ch. Raji Reddy, S. Chandrasekhar and Dong-Soo Shin
Practicable Synthesis of 1-(1-Phenylethyl)-1H-pyrido[2,3-b][1,4]oxazine
Bull. Korean Chem. Society, 2007, 28, 2486-2488.
23. S. Chandrasekhar,* K. Vijeender, G. Chandrashekar and Ch. Raji Reddy Towards synthesis of Palmerolide A: asymmetric synthesis of C1-C14 fragment
Tetrahedron: Asymmetry, 2007, 18, 2473-2478
22. Ch. Raji Reddy,* B. Mahipal and Y. Srinivasa Rao
A new and efficient method for the synthesis of N-acyl sulfonamides under Lewis acid catalysis
Tetrahedron Letters, 2007, 48, 7528-7532
21. Ch. Raji Reddy,* P. Phani Madhavi and A. Syamprasad Reddy Molybdenum(V) chloride-catalyzed amidation of secondary benzyl alcohols with sulfonamides and Carbamates
Tetrahedron Letters, 2007, 48, 7169-7172
20. S. Chandrasekhar,* Ch. Lohitha Rao, Ch. Nagesh, Ch. Raji Reddy and B. Sridhar
Inter and intramolecular copper(I)-catalyzed 1,3-dipolar cycloaddition of azido-alkynes: Synthesis of furanotriazole macrocycles
Tetrahedron Letters, 2007, 48, 5869-5872
19. S. Chandrasekhar,* Debjit Basu and Ch. Raji Reddy
Palladium catalyzed reduction of N-Boc-indoles using polymethyl hydrosiloxane
Synthesis, 2007, 1509-1512.
18. Ch. Raji Reddy,* K. Vijeender, P. Bibhuti Bhusan, P. Phani Madhavi and S. Chandrasekhar
Reductive N-alkylation of aromatic amines and nitro compounds with nitriles using Polymethyl hydroxiloxane
Tetrahedron Letters, 2007, 48, 2765-2768
17. S. Chandrasekhar,* G. P. K. Reddy, Ch. Nagesh and Ch. Raji Reddy
A Novel one-pot conversion of amines to homologated esters in poly(ethylene glycol)
Tetrahedron Letters, 2007, 48, 1269-1271
16. Ch. Raji Reddy,* N. Kiranmai, G. S. Kiran Babu, G. Dattatreya Sarma, B. Jagadeesh and S. Chandrasekhar
Palladium catalyzed addition of hydroxylamine derivatives to Baylis Hillman acetate adducts
Tetrahedron Letters, 2007, 48, 215-218
PhD & POST - DOC WORK
15. Ch. Raji Reddy, Amar G. Ch., Rajashaker K., J. C. Jung, E. B. Watkins and M. A. Avery,*
The trimethylsilyl xylyl (TIX) ether: A useful protecting group for alcohols
Tetrahedron, 2005, 61, 1289-1295.
14. Amar G. Ch., Ch. Raji Reddy, E. B. Watkins and M. A. Avery,*
Addition of lithioimidazoles to isocyanates followed by Pd-coupling: access to 4-substituted imidazole-2,5-dicarboxamides,
Tetrahedron Letters, 2004, 45, 1869-1872
13. Amar G. Ch., Ch. Raji Reddy, E. B. Watkins and M. A. Avery,*
First synthesis of antimalarial Machaeriols A and B
Tetrahedron Letters, 2004, 45, 1689-1691
12. S Chandrasekhar,* G Chandrashekar and Ch. Raji Reddy Tris(pentafluorophenyl)borane catalyzed Ferrier azaglycosyla-tion with sulfonamides and carbamates
Tetrahedron Letters, 2004, 45, 6481-6484
11. S. Chandrasekhar,* Ch. Raji Reddy and B. Nagendra Babu
Single step conversion of N-Benzyl, N-trityl, N-Diphenyl methyl amines to tert.Butyl carbamates using PMHS
Tetrahedron Letters, 2003, 44, 2057-2059
10. S. Chandrasekhar, Ch. Raji Reddy and B. Nagendra Babu
Rapid defunctionalization of carbonyl functionality to methylene using polymethyl-hydrosiloxane-B(C6F5)3
J. Org. Chem., 2002, 67, 9080-9082
9. S. Chandrasekhar,* Ch. Raji Reddy, B. Nagendra Babu and G. Chandrashekar
Highly efficient cleavage of epoxides catalyzed by B(C6F5)3
Tetrahedron Letters, 2002, 43, 3801-3803
8. S. Chandrasekhar,* and Ch. Raji Reddy
Towards a synthesis of epothilone A: Asymmetric synthesis of C(1)-C(6) and C(7)-C(15) fragments
Tetrahedron: Asymmetry, 2002, 13, 261-268
7. S. Chandrasekhar,* Ch. Raji Reddy, R. Jagadeeshwar Rao and
J. Madusudana Rao
Efficient and Chemoselective Deoxygenation of Amine N- Oxides using Polymethyl-hydrosiloxane
Synlett, 2002, 349-351
6. S. Chandrasekhar,* Ch. Raji Reddy and R. Jagadeeshwar Rao
Unprecedented Direct Conversion of N-N and N=N bonds to N-(tert-Bytyloxy)-carbamates
Synlett, 2001, 1561-1562.
5. S. Chandrasekhar,* Ch. Raji Reddy and R. Jagadeeshwar Rao
Facile and selective cleavage of allyl ethers, amines and esters using polymethyl hydrosiloxane- ZnCl2/Pd (PPh3)4
Tetrahedron, 2001, 57, 3435-3438
4. S. Chandrasekhar,* Ch. Raji Reddy and M. Ahmed
A Single Step Reductive Amination of Carbonyl Compounds with Polymethyl-hydrosiloxane-Ti(OiPr)4
Synlett, 2000, 1655-1657
3. S. Chandrasekhar*, L. Chandraiah, Ch. Raji Reddy and M. Venkat Reddy
Direct Conversion of Azides and Benzylcarbamates to t-butyl Carbamates using Polymethyl-hydrosiloxane and Pd-C
Chemistry Letters, 2000, 780-781.
2. S. Chandrasekhar,* Ch. Raji Reddy and M. Venkat Reddy
DDQ as a versatile reagent for the oxidative cleavage of tosyl hydrazones and oximes
Chemistry Letters, 2000, 430-431
1. S. Chandrasekhar*, Y. Ravindra Reddy and Ch. Raji Reddy
Regioselective Reductive Opening of 1,2 and 1,3 Benzylidene Acetals
Chemistry Letters, 1998, 1273-1274.